کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
10528936 | 960762 | 2005 | 10 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Potentiometric flow injection analysis of dicyclomine hydrochloride in serum, urine and milk
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آنالیزی یا شیمی تجزیه
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Potentiometric flow injection analysis of dicyclomine hydrochloride in serum, urine and milk Potentiometric flow injection analysis of dicyclomine hydrochloride in serum, urine and milk](/preview/png/10528936.png)
چکیده انگلیسی
Five plastic membrane electrodes for the determination of dicyclomine hydrochloride (DcCl) were fabricated and fully characterized in terms of composition, life span, usable pH range, working concentration range and temperature. The membranes of these electrodes consist of dicyclominium-silicotungstate (Dc-ST), silicomolybdate (Dc-SM), phosphotungstate (Dc-PT), phosphomolybdate (Dc-PM) or tetraphenylborate (Dc-TPB) ion-associations dispersed in PVC matrix with dibutyl phthalate plasticizer. The electrodes showed near-Nernstian response over the concentration range of 4.0 Ã 10â6 to 1.0 Ã 10â2 M DcCl and applied to the potentiometric determination of dicyclominium ion in pharmaceutical preparations, serum, urine and milk in batch and flow injection (FI) conditions with average recoveries of 96.1-102.7% and relative standard deviation of 0.055-1.994%. The electrodes exhibit good selectivity for DcCl with respect to a large number of inorganic cations, organic cations, sugars and amino acids. The sensitivities of these electrodes are high enough to measure as low as 1.73 μg/ml of DcCl which permit the determination of the Ksp values of the ion-associates used. The proposed potentiometric methods offer the advantages of simplicity, accuracy, automation feasibility and applicability to turbid and colored sample solutions.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Analytica Chimica Acta - Volume 532, Issue 1, 7 March 2005, Pages 79-88
Journal: Analytica Chimica Acta - Volume 532, Issue 1, 7 March 2005, Pages 79-88
نویسندگان
H. Ibrahim, Y.M. Issa, Hazem M. Abu-Shawish,