Antigen-antibody interface properties: Composition, residue interactions, and features of 53 non-redundant structures

► Ag-Ab interfaces are a rich source of information about Ag folding. ► 53 non-redundant 3D structures of Ag-Ab complexes are computationally analyzed. ► Interface features, composition, interaction frequencies averaged and summarized. ► Confirms importance of paratope aromatics. ► Provides scaling of the importance of all amino acids and their interactions.