Stabilization of anthocyanin and skullcap flavone complexes - Investigations with computer simulation and experimental methods

► We determined anthocyanins of honeysuckle concentrates stabilized with skullcap flavone. ► Theoretical study of copigmentation was conducted with molecular dynamics methods. ► The sites responsible for the stabilization of anthocyanin-flavon complex were determined. ► The stacking of cyanidin-baicalin complex is formed by hydrogen bonds and water bridges. ► The conducted research confirmed stabilizing influence of skullcap flavones on anthocyanins.