Anti-inflammatory effect and modulation of cytochrome P450 activities by Artemisia annua tea infusions in human intestinal Caco-2 cells

► Characterisation and effect of Artemisia annua extracts on intestinal function. ► Rosmarinic and chlorogenic acids identified as the main phenolic compounds. ► Anti-inflammatory effect of extracts and rosmarinic acid, but not artemisinin. ► Inhibition of CYP3A4 and 1A1 activity by extracts. ► A. annua phenolic content could reduce inflammation in malaria or chronic diseases.