Physiochemical properties and prolonged release behaviours of chitosan-denatured β-lactoglobulin microcapsules for potential food applications

► Prolonged release in the GI tract promotes better intestinal absorption. ► Denatured β-lactoglobulin (βlg) is resistant to pepsin hydrolysis. ► Chitosan (CS) prolongs residence time due to formation of a viscous gel layer. ► Complexation between βlg and CS forms a double-wall structure. ► CS/βlg shell encapsulates bioactives for prolonged release in the GI tract.