Cardiovascular protection of deep-seawater drinking water in high-fat/cholesterol fed hamsters

► DSW contains high K, Ca, and Mg, and a better ratio of Mg/Ca. ► DSW decreases serum and liver lipids, and serum lipid peroxidation. ► DSW increased faecal lipid excretion in a high-fat/cholesterol diet. ► DSW upregulates gene expressions of LDL receptor and CYP7A1. ► DSW does not affect heart rates and blood pressures.