A novel chemiluminescence immunoassay of staphylococcal enterotoxin B using HRP-functionalised mesoporous silica nanoparticle as label

► We used HRP and Ab2-functionalised mesoporous silica nanosphere as labels. ► The synthesised MSN were good monodispersed and uniformity. ► The method possesses good reproducibility and desired analytical performance. ► This strategy is a novel, sensitive method to detect SEB in practical samples.