A one-pot ultrasound-assisted water extraction/cyclodextrin encapsulation of resveratrol from Polygonum cuspidatum

► A novel extraction method of resveratrol from the roots of Polygonum cuspidatum has been reported. ► Excellent results have been achieved with ultrasound-assisted extraction. ► The capability of cyclodextrins to form inclusion complexes, allow the use of water as extraction media. ► The excellent radical scavenging activity of these extracts was evaluated by DPPH and ORACFL assay.