Protein-binding and antioxidant potential of phenolics of mangosteen fruit (Garcinia mangostana)

► Mangosteen fruit phenolics display strong affinities for proteins. ► Phenolics from peel and rind are excellent protein precipitants. ► The static quenching is the dominant mode of quenching of BSA fluorescence by mangosteen fruit phenolics. ► Mangosteen phenolics occupy two binding sites on BSA molecules that are located most likely in or near both tryptophan residues in the BSA molecule acting as intrinsic fluorescence probe.