کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
10554438 | 967963 | 2005 | 4 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Spectrophotometric determination of oxiconazole in topical lotion using methyl orange
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آنالیزی یا شیمی تجزیه
پیش نمایش صفحه اول مقاله

چکیده انگلیسی
A spectrophotometric method is described for the determination of oxiconazole in raw material and in topical lotion. This method is based on the reaction of the oxiconazole with methyl orange in buffered aqueous solution of citric acid at pH 2.3. The chromogen, being extractable with dichloromethane, could be measured quantitatively with maximum absorption at 427 nm. The Lambert-Beer law was obeyed in the concentration range of 4.0-14.0 μg mlâ1. A prospective validation of the method showed that the method was linear (r = 0.9995), precise (intra-day: CV = 1.57% and inter-day: CV = 1.50%) and accurate (mean recoveries: 99.69%). The results compared favourably with those of the HPLC method.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Pharmaceutical and Biomedical Analysis - Volume 37, Issue 4, 1 April 2005, Pages 639-642
Journal: Journal of Pharmaceutical and Biomedical Analysis - Volume 37, Issue 4, 1 April 2005, Pages 639-642
نویسندگان
Julie Milano, Simone Gonçalves Cardoso,