iTRAQ-based quantitative proteomic analysis of Thermobifida fusca reveals metabolic pathways of cellulose utilization

► Thermobifida fusca is a thermophilic cellulose degrading bacterium useful in bioenergy sector. ► This report highlights the protein expression involved in cellular processes during cellulose utilization. ► The data could be useful for metabolic pathway manipulation to enhance cellulose degradation potential. ► Proteins involved in central metabolism of sugars and amino acids were induced during cellulose degradation. ► Of 30 identified ribosomal proteins, 29 were up-regulated during cellulose hydrolysis.