Proteomics in asthma and COPD phenotypes and endotypes for biomarker discovery and improved understanding of disease entities

► Asthma and COPD are diseases comprising of multiple phenotypes. ► The complexity of asthma and COPD is challenging to study by proteomics. ► Improved phenotyping may improve future proteomic studies. ► Proteomic studies of disease phenotypes may reveal pathobiological mechanisms.