Comparative proteome analysis of acute myeloid leukemia with and without maturation

► AML-M1 and M2 blasts were compare with 2DE/MS. ► Studies involved 38 AML-M/M2 patients and 17 healthy volunteers. ► Both BM- and PB-derived cells were analyzed. ► Several sets of potential AML-M1/M2-specific biomarkers were identified.