کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
10560893 | 969755 | 2005 | 5 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Two-photon fluorescence excitation using an integrated optical microcavity: a promising tool for biosensing of natural chromophores
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آنالیزی یا شیمی تجزیه
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Two-photon fluorescence excitation using an integrated optical microcavity: a promising tool for biosensing of natural chromophores Two-photon fluorescence excitation using an integrated optical microcavity: a promising tool for biosensing of natural chromophores](/preview/png/10560893.png)
چکیده انگلیسی
Application of an integrated optics (IO) microcavity (MC) for evanescent excitation of two-photon excited fluorescence (TPF) is demonstrated. The MC provides a high local intensity, which is required for the TPF, because of resonant enhancement of the intracavity power and a strong two-dimensional confinement of the guided mode. Numerical estimations show a large increase, by more than a factor of 104 of the TPF intensity at the MC compared to a conventional straight waveguide. This will lead to a significant improvement of the detection limits of UV-absorbing chromophores (down to 10â8Â M) when using the MC as a biosensor. Feasibility of TPF excitation using an IO MC is confirmed experimentally for the first time.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Talanta - Volume 65, Issue 5, 15 March 2005, Pages 1086-1090
Journal: Talanta - Volume 65, Issue 5, 15 March 2005, Pages 1086-1090
نویسندگان
Evgueni Krioukov, Dion Klunder, Alfred Driessen, Jan Greve, Cees Otto,