Reaction of platinum(II) diamine and triamine complexes with selenomethionine

► [Pt(dien)Cl]Cl has kinetic selectivity for selenomethionine over methionine. ► [Pt(Me4en)(D2O)2]2+ has stereoselectivity during chelation of selenomethionine. ► [Pt(en)(D2O)2]2+ can form a variety of products with selenomethionine. ► Displacement of the en ligand occurs when two selenomethionines are coordinated.