کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
10573958 | 976443 | 2011 | 7 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
The triphenyltin(VI) complexes of NSAIDs and derivatives. Synthesis, crystal structure and antiproliferative activity. Potent anticancer agents
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی معدنی
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![عکس صفحه اول مقاله: The triphenyltin(VI) complexes of NSAIDs and derivatives. Synthesis, crystal structure and antiproliferative activity. Potent anticancer agents The triphenyltin(VI) complexes of NSAIDs and derivatives. Synthesis, crystal structure and antiproliferative activity. Potent anticancer agents](/preview/png/10573958.png)
چکیده انگلیسی
The novel triphenyltin(IV)esters of flufenamic acid (1), Hflu, [Ph3Sn(flu)] (2), and of [2-(2,3-dichlorophenylamino)benzoic acid] (3), Hdcpa, [Ph3Sn(dcpa)] (4) have been characterized by spectroscopic studies. The crystal and molecular structures of [SnPh3(dcpa)(dmso)] is described. The in vitro cytotoxic activity of 1-4 and of the related NSAIDs has been evaluated against cancer cell lines MCF-7, T-24, A-549 and L-929. The results of this study represent the discovery of triphenyltin(IV)esters as a potential novel class of anticancer agents.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Inorganic Biochemistry - Volume 105, Issue 2, February 2011, Pages 195-201
Journal: Journal of Inorganic Biochemistry - Volume 105, Issue 2, February 2011, Pages 195-201
نویسندگان
Vaso Dokorou, Alexandra Primikiri, Dimitra Kovala-Demertzi,