4-Functionalized 1,3-diarylpyrazoles bearing 6-aminosulfonylbenzothiazole moiety as potent inhibitors of carbonic anhydrase isoforms hCA I, II, IX and XII

Novel heterocyclic compounds bearing 6-aminosulfonylbenzothiazole moiety at position 1 of 4-functionalized pyrazole ring showed moderate to excellent carbonic anhydrase hCA I, II, IX and hCA XII inhibitory efficiency.