Anti-cancer activity of 5-O-alkyl 1,4-imino-1,4-dideoxyribitols

The oleyl derivative 13 (IC50 ∼2 M) is cytotoxic toward SKBR3 (breast cancer) cells. 13 also inhibits (IC50 ∼8 M) growth of JURKAT (acute lymphoblastic leukemia) cells.