کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
10586368 981390 2011 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Isolation of the β-galactosphingolipid coniferoside using a tumor cell proteome reverse affinity protocol
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آلی
پیش نمایش صفحه اول مقاله
Isolation of the β-galactosphingolipid coniferoside using a tumor cell proteome reverse affinity protocol
چکیده انگلیسی
New approaches are vital to the development of marine natural products (MNP) as therapeutic leads. One of the more time consuming aspects of MNP research arises in the connection between structure and function. Here, we describe an isolation protocol that adapts tumor cell proteomes as a vehicle for MNP isolation therein uniting structural and functional analysis. Application of this method to extracts of the sponge Agelas conifera led to the isolation of a unique poly-hydroxybutyrated β-galactosphingolipid, coniferoside.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Bioorganic & Medicinal Chemistry - Volume 19, Issue 22, 15 November 2011, Pages 6645-6653
نویسندگان
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