کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
10586396 | 981390 | 2011 | 10 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Synthesis and in vitro cytotoxic activity of novel pyrazolo[3,4-d]pyrimidines and related pyrazole hydrazones toward breast adenocarcinoma MCF-7 cell line
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آلی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Synthesis and in vitro cytotoxic activity of novel pyrazolo[3,4-d]pyrimidines and related pyrazole hydrazones toward breast adenocarcinoma MCF-7 cell line Synthesis and in vitro cytotoxic activity of novel pyrazolo[3,4-d]pyrimidines and related pyrazole hydrazones toward breast adenocarcinoma MCF-7 cell line](/preview/png/10586396.png)
چکیده انگلیسی
The present work reports the synthesis of novel pyrazolo[3,4-d]pyrimidines and related pyrazole hydrazones and the evaluation of their cytotoxic activity against human breast cancer cell MCF-7. In addition, the effect of selected compounds on the activities of free-radical-metabolizing enzymes as well as the levels of oxidative stress parameters in MCF-7 cells was estimated.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Bioorganic & Medicinal Chemistry - Volume 19, Issue 22, 15 November 2011, Pages 6808-6817
Journal: Bioorganic & Medicinal Chemistry - Volume 19, Issue 22, 15 November 2011, Pages 6808-6817
نویسندگان
Ghaneya Sayed Hassan, Hanan Hassan Kadry, Sahar Mahmoud Abou-Seri, Mamdouh Moawad Ali, Abeer Essam El-Din Mahmoud,