کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
10587198 | 981425 | 2012 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Tea catechins and flavonoids from the leaves of Camellia sinensis inhibit yeast alcohol dehydrogenase
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آلی
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
Four new quercetin acylglycosides, designated camelliquercetisides A-D, quercetin 3-O-[α-l-arabinopyranosyl(1â3)][2-Oâ³-(E)-p-coumaroyl][β-d-glucopyranosyl(1â3)-α-l-rhamnopyranosyl(1â6)]-β-d-glucoside (17), quercetin 3-O-[2-Oâ³-(E)-p-coumaroyl][β-d-glucopyranosyl(1â3)-α-l-rhamnopyranosyl(1â6)]-β-d-glucoside (18), quercetin 3-O-[α-l-arabinopyranosyl(1â3)][2-Oâ³-(E)-p-coumaroyl][α-l-rhamnopyranosyl(1â6)]-β-d-glucoside (19), and quercetin 3-O-[2-Oâ³-(E)-p-coumaroyl][α-l-rhamnopyranosyl(1â6)]-β-d-glucoside (20), together with caffeine and known catechins, and flavonoids (1-16) were isolated from the leaves of Camellia sinensis. Their structures were determined by spectroscopic (1D and 2D NMR, IR, and HR-TOF-MS) and chemical methods. The catechins and flavonoidal glycosides exhibited yeast alcohol dehydrogenase (ADH) inhibitory activities in the range of IC50 8.0-70.3 μM, and radical scavenging activities in the range of IC50 1.5-43.8 μM, measured by using the 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Bioorganic & Medicinal Chemistry - Volume 20, Issue 7, 1 April 2012, Pages 2376-2381
Journal: Bioorganic & Medicinal Chemistry - Volume 20, Issue 7, 1 April 2012, Pages 2376-2381
نویسندگان
Md. Maniruzzaman Manir, Jeong Kee Kim, Byeong-Gon Lee, Surk-Sik Moon,