A new antifungal and cytotoxic C-methylated flavone glycoside from Picea neoveitchii

A new C-methylated flavone glycoside, 5,7-dihydroxy-3-methoxy-6-C-methylflavone 8,4′-di-O-β-d-glucopyranoside (1), together with seven known compounds (2-9) were isolated from the twigs and leaves of Picea neoveitchii Mast. The cytotoxicities of the isolated compounds on Spodoptera litura Fabricius cell were evaluated by MTT assay and their antifungal activities were evaluated by disc diffusion method. Three of these compounds were isolated from the Pinaceae family for the first time.