Binding of β-d-glucopyranosyl bismethoxyphosphoramidate to glycogen phosphorylase b: kinetic and crystallographic studies

β-d-Glucopyranosyl bismethoxyphosphoramidate, a glucosyl phosphate analogue, was tested for inhibition of and binding to glycogen phosphorylase b. The structural basis of inhibition is presented by analysing the crystal structure of the enzyme in complex with the inhibitor at 1.83 Å resolution.