Preliminary investigation of 6,7-dihydropyrazolo[1,5-a]pyrazin-4-one derivatives as a novel series of mGlu5 receptor positive allosteric modulators with efficacy in preclinical models of schizophrenia

Preliminary investigation of 6,7-dihydropyrazolo[1,5-a]pyrazin-4-one derivatives as a novel series of mGlu5 receptor positive allosteric modulators with efficacy in preclinical models of schizophrenia

Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Bioorganic & Medicinal Chemistry Letters - Volume 26, Issue 2, 15 January 2016, Pages 429-434

Susana Conde-Ceide, Jesús Alcázar, Sergio A. Alonso de Diego, Silvia López, María Luz Martín-Martín, Carlos M. Martínez-Viturro, Miguel-Angel Pena, Han Min Tong, Hilde Lavreysen, Claire Mackie, Thomas M. Bridges, J. Scott Daniels,