Discovery of highly potent and selective Bruton's tyrosine kinase inhibitors: Pyridazinone analogs with improved metabolic stability

Discovery of highly potent and selective Bruton's tyrosine kinase inhibitors: Pyridazinone analogs with improved metabolic stability

Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Bioorganic & Medicinal Chemistry Letters - Volume 26, Issue 2, 15 January 2016, Pages 575-579

Wendy B. Young, James Barbosa, Peter Blomgren, Meire C. Bremer, James J. Crawford, Donna Dambach, Charles Eigenbrot, Steve Gallion, Adam R. Johnson, Jeffrey E. Kropf, Seung H. Lee, Lichuan Liu, Joseph W. Lubach, Jen Macaluso, Pat Maciejewski,