کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
10595164 981861 2012 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Design, synthesis, and in vitro antiproliferative activity of novel Dasatinib derivatives
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آلی
پیش نمایش صفحه اول مقاله
Design, synthesis, and in vitro antiproliferative activity of novel Dasatinib derivatives
چکیده انگلیسی
Two series of novel Dasatinib derivatives have been designed and synthesized, with their in vitro cytostatic effect screened on human chronic myeloid leukemia cell line K562 and human myeloid leukemia cell line U937. Compared to the contrast drug Dasatinib, several compounds were found to demonstrate more potent antitumor activities.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Bioorganic & Medicinal Chemistry Letters - Volume 22, Issue 2, 15 January 2012, Pages 806-810
نویسندگان
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