Analysis of structural heterogeneity of fucoidan from Hizikia fusiforme by ES-CID-MS/MS

► A heterogeneous fucoidan was isolated and purified from brown alga Hizikia fusiforme. ► The sequence of oligosaccharides prepared by partial acid hydrolysis of fucoidan was determined by ES-CID-MS/MS. ► A repeating disaccharide unit of [→4GlcAβ1,2Manα1→] was the backbone structure of the fucoidan.