Inclusion complex of methyl-β-cyclodextrin and olanzapine as potential drug delivery system for schizophrenia

► Olanzapine, a high cost drug, is the most important antipsychotic drug on the market. ► Olanzapine has low aqueous solubility, affecting its dissolution and absorption. ► Methyl-β-cyclodextrin was the most effective alternative to olanzapine drug delivery. ► The product developed has higher stability and dissolution rate than the drug alone.