Complexation of copper(II) with chitosan nanogels: Toward control of microbial growth

► Elaboration of stable chitosan nanogels loaded with large amounts of copper(II) ions. ► Chitosan-copper(II) complex controlled the release of copper(II) as a function of the pH. ► Biodegradation of chitosan nanogels, using chitosanolytic enzymes. ► Synergy of antifungal activities between copper(II) and chitosan (solution or dispersion).