Hydrogels and electrospun nanofibrous scaffolds of N-methylene phosphonic chitosan as bioinspired osteoconductive materials for bone grafting

► Genipin crosslinked N-methylene phosphonic chitosan (NMPC) in a concentration dependent manner. ► Solution property based optimization led to uniform NMPC blend nanofibers. ► Treatment of NMPC blend nanofibers with SBF provided a uniformly mineralized matrix. ► Both gelation and electrospinning processes led to bicompatible NMPC matrices suitable for bone graft applications.