PEGylated starch acetate nanoparticles and its potential use for oral insulin delivery

► Hydrophilic polyethylene glycol was conjugated with hydrophobic starch acetate. ► Nanoparticles were formed by self aggregation of this polymer conjugate. ► These nanoparticles were highly bioadhesive compared to chitosan. ► These nanoparticles can incorporate insulin and release it in a sustained manner.