Coaxial electrospun poly(lactic acid)/chitosan (core/shell) composite nanofibers and their antibacterial activity

► The electrospinning of CS has been a challenge because of its high viscosity in solution and its polycationic possession. ► The coaxial electrospinning method was able to facilitate the fabrication of double-layer PLA/CS nanofibers by employing PLA and CS in the core and shell part, respectively. ► The complete core/shell structure of the PLA/CS nanofibers were obtained at shell and core feed rates of 5 μL/min and less than 2 μL/min, respectively. ► The fabricated core/shell nanofibers showed antibacterial activity against Escherichia coli.