کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
10608560 | 984158 | 2011 | 8 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
PH-responsive nano-assemblies of amino poly(glycerol methacrylate)
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آلی
پیش نمایش صفحه اول مقاله
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چکیده انگلیسی
Both linear and star-shaped poly(glycidyl methacrylate) (PGMA) polymers were modified with different amines and used to prepare pH-sensitive nano-assemblies. Nanoprecipitation technique and dialysis method were used to prepare the polymeric nanoparticles. These nano-assemblies showed pH-sensitive disassociation properties under an acidic condition. The polymers were quite effective in encapsulation of Congo red (CR). Atom force microscopy images showed that the nanoparticles prepared using nanoprecipitation technique are spherical before and after encapsulation of CR. The disassociation pH, encapsulation efficiency, loading capacity and release properties of these polymers were found to depend on their backbone architecture and the amine type. By adjusting of these factors, such type of polymers hold promise as an interesting drug delivery vehicle.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: European Polymer Journal - Volume 47, Issue 6, June 2011, Pages 1232-1239
Journal: European Polymer Journal - Volume 47, Issue 6, June 2011, Pages 1232-1239
نویسندگان
Gao Hui, Ma Yanan, Lu Xueyou, Liang Yongri, Chen Baoquan, Ma Jianbiao,