کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
10609870 | 984736 | 2011 | 8 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Biocompatible cryogels of thermosensitive polyglycidol derivatives with ultra-rapid swelling properties
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آلی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Biocompatible cryogels of thermosensitive polyglycidol derivatives with ultra-rapid swelling properties Biocompatible cryogels of thermosensitive polyglycidol derivatives with ultra-rapid swelling properties](/preview/png/10609870.png)
چکیده انگلیسی
Novel thermosensitive macroporous cryogels, based on various hydrophobically modified high molar mass (HMM) polyglycidol precursors, were synthesized using the UV-irradiation technique. The method involved the preparation of a semi-dilute aqueous solution of thermosensitive poly(glycidol-co-ethyl glycidyl carbamate) (PGL-Et), subsequent freezing at a moderately negative temperature (â20 °C) and irradiation with UV light. All PGL-Et cryogels had a spongy-like structure of smooth polymer walls surrounding interconnected macroscopic pores. Consequently, the cryogels exhibited temperature triggered, reversible, ultra-rapid volume phase transition (VPT) from a swollen to deswollen state within 20-25 s. The VPT temperature of the PGL-Et cryogels was strongly dependent on the degree of modification of the PGL precursors and it decreased proportionally with increased ethyl glycidyl carbamate content. The PGL-Et cryogels were used as a scaffold for skin cell (fibroblast) adhesion. Adhesion and proliferation tests indicated that the gels were good supports for cell cultivation.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: European Polymer Journal - Volume 47, Issue 5, May 2011, Pages 981-988
Journal: European Polymer Journal - Volume 47, Issue 5, May 2011, Pages 981-988
نویسندگان
Petar Petrov, Alicja Utrata-WesoÅek, Barbara Trzebicka, Christo B. Tsvetanov, Andrzej Dworak, Jacek AnioÅ, Aleksander SieroÅ,