کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
10691367 | 1019595 | 2015 | 9 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Focused Low-Intensity Pulsed Ultrasound Enhances Bone Regeneration in Rat Calvarial Bone Defect through Enhancement of Cell Proliferation
ترجمه فارسی عنوان
سونوگرافی پالس شده با شدت کم متمرکز بهبود استخوان را در نقص استخوان کلورالی موش صحرایی از طریق افزایش تکثیر سلولی
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کلمات کلیدی
سونوگرافی پالس با شدت کم متمرکز، شکستگی استخوان کبدی، بازسازی استخوان، گسترش استئوسیت،
موضوعات مرتبط
مهندسی و علوم پایه
فیزیک و نجوم
آکوستیک و فرا صوت
چکیده انگلیسی
A number of studies have reported the therapeutic potential of low-intensity pulsed ultrasound (LIPUS) for induction of bone repair. This study investigated whether bone regeneration might be enhanced by application of focused LIPUS to selectively stimulate fractured calvarial bone. To accomplish this, bone defects were surgically created in the middle of the skull of rats that were subsequently exposed to focused LIPUS. Bone regeneration was assessed by repeated computed tomography imaging after the operation, as well as histologic analysis with calcein, hematoxylin and eosin and proliferating cell nuclear antigen assay. At 6Â wk after surgery, bone formation in the focused LIPUS-treated group improved significantly relative to the control. Interestingly, new bone tissue sprouted from focused LIPUS target points. Histologic analysis after exposure to focused LIPUS revealed that proliferating cells were significantly increased relative to the control. Taken together, these results suggest that focused LIPUS can improve re-ossification through enhancement of cell proliferation in calvarial defect sites.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Ultrasound in Medicine & Biology - Volume 41, Issue 4, April 2015, Pages 999-1007
Journal: Ultrasound in Medicine & Biology - Volume 41, Issue 4, April 2015, Pages 999-1007
نویسندگان
Yu Jin Jung, Ran Kim, Hyun-Joo Ham, Sang In Park, Min Young Lee, Jongmin Kim, Jihwan Hwang, Moon-Seo Park, Seung-Schik Yoo, Lee-So Maeng, Woochul Chang, Yong-An Chung,