کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
10691624 1019602 2014 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Treatment with Focused Ultrasound Waves Softens the Rat Cervix During Pregnancy
ترجمه فارسی عنوان
درمان با امواج اولتراسوند متمرکز موجب شل شدن رحم در حین بارداری می شود
کلمات کلیدی
تحریک سونوگرافی متمرکز، نرم شدن و رسیدن سرویکس، اثر زیستی اولتراسوند،
موضوعات مرتبط
مهندسی و علوم پایه فیزیک و نجوم آکوستیک و فرا صوت
چکیده انگلیسی
Application of focused ultrasound stimulation (FUS) to the rat cervix during pregnancy has significant physiologic effects. One-millisecond-long pulses of 680-kHz ultrasound with a repetition frequency of 25 Hz, at ISPTA (spatial-peak, temporal-average intensity) of 1, 2 and 4W/cm2, were applied to the rat abdomen over the cervix. FUS produced a significant change in cervical elasticity known as softening, which is part of the ripening process, comparable to the degree seen just before delivery. Timed-pregnant Sprague-Dawley rats (n = 40) were used. During gestation, the FUS system was applied to the cervix for variable times up to 1 h. Daily measurements of cervix light-induced florescence were made to estimate changes in softening. In addition, cervical stretch estimates of softening were made of isolated cervices of control and FUS-treated rats to measure distensiblity. The ultrasound power with ISPPA (spatial-peak, pulse-average intensity) of 40 W/cm2 was considered tolerable; the U.S. Food and Drug Administration regulatory limit is 190 W/cm2 for both the body periphery and the fetus. This is the first report of alterations induced by ultrasound in the connective tissue of the cervix and suggests the therapeutic application of ultrasound for the facilitation of labor and delivery.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Ultrasound in Medicine & Biology - Volume 40, Issue 9, September 2014, Pages 2107-2112
نویسندگان
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