کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
10691953 1019614 2013 10 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Potential Femoral Head Osteonecrosis Model Induced by High-Intensity Focused Ultrasound
ترجمه فارسی عنوان
مدل استئوآرکستیک سرنشین سرطان فمورال مبتلا به سونوگرافی متمرکز با شدت بالا
کلمات کلیدی
سونوگرافی متمرکز با شدت بالا، استئونکروز، سر فمور سگ، مدل های ریاضی،
موضوعات مرتبط
مهندسی و علوم پایه فیزیک و نجوم آکوستیک و فرا صوت
چکیده انگلیسی
Osteonecrosis of the femoral head is a common disease that can result in complex hip replacement. To evaluate potential treatments, a model that consistently creates osteonecrosis is needed. We studied and demonstrated the possibility of developing an osteonecrosis model using high-intensity focused ultrasound (HIFU) on canine femora in vitro. To achieve these goals, the temperature in the medullary cavity of the femoral head was measured. A phenomenological model was developed to fit the measured temperature variations with the HIFU parameters for similar HIFU experiments on femoral heads. The average temperature discrepancy between model and measured values was less than 0.83°C. Histology confirmed that the temperature in the medullary cavity can be elevated to a level at which an acute thermal injury is created. HIFU has the potential to be used in a non-invasive model of osteonecrosis.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Ultrasound in Medicine & Biology - Volume 39, Issue 6, June 2013, Pages 1056-1065
نویسندگان
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