کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
10692270 1019660 2005 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
In vitro ablation of cardiac valves using high-intensity focused ultrasound
موضوعات مرتبط
مهندسی و علوم پایه فیزیک و نجوم آکوستیک و فرا صوت
پیش نمایش صفحه اول مقاله
In vitro ablation of cardiac valves using high-intensity focused ultrasound
چکیده انگلیسی
The purpose of this study was to evaluate the possibility of using high-intensity focused ultrasound (US), or HIFU, to create lesions in cardiac valves in vitro. Calf mitral valves and aortic valves were examined. Focused US energy was applied with an operating frequency of 4.67 MHz at a nominal acoustic power of 58 W for 0.2, 0.3 and 0.4 s at 4-s intervals. Mitral valve perforation was achieved with 20.8 ± 3.7 exposures of 0.2 s, 15.4 ± 2.1 exposures of 0.3 s or 11.2 ± 2.3 exposures of 0.4 s. Aortic valve perforation was achieved with 13.3 ± 2.4 exposures of 0.2 s, 10.3 ± 2.2 exposures of 0.3 s or 8.4 ± 1.8 exposures of 0.4 s. The mean diameter of the perforated area was 1.09 ± 0.11 mm. The lesions were slightly discolored and coagulation of tissue around the perforation was observed. HIFU was successful in perforating cardiac valves. With further refinement, HIFU may prove useful for valvulotomy or valvuloplasty. (E-mail: otsukaryo@aol.com)
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Ultrasound in Medicine & Biology - Volume 31, Issue 1, January 2005, Pages 109-114
نویسندگان
, , , , , , , , , , , , ,