کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
10692270 | 1019660 | 2005 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
In vitro ablation of cardiac valves using high-intensity focused ultrasound
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
فیزیک و نجوم
آکوستیک و فرا صوت
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چکیده انگلیسی
The purpose of this study was to evaluate the possibility of using high-intensity focused ultrasound (US), or HIFU, to create lesions in cardiac valves in vitro. Calf mitral valves and aortic valves were examined. Focused US energy was applied with an operating frequency of 4.67 MHz at a nominal acoustic power of 58 W for 0.2, 0.3 and 0.4 s at 4-s intervals. Mitral valve perforation was achieved with 20.8 ± 3.7 exposures of 0.2 s, 15.4 ± 2.1 exposures of 0.3 s or 11.2 ± 2.3 exposures of 0.4 s. Aortic valve perforation was achieved with 13.3 ± 2.4 exposures of 0.2 s, 10.3 ± 2.2 exposures of 0.3 s or 8.4 ± 1.8 exposures of 0.4 s. The mean diameter of the perforated area was 1.09 ± 0.11 mm. The lesions were slightly discolored and coagulation of tissue around the perforation was observed. HIFU was successful in perforating cardiac valves. With further refinement, HIFU may prove useful for valvulotomy or valvuloplasty. (E-mail: otsukaryo@aol.com)
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Ultrasound in Medicine & Biology - Volume 31, Issue 1, January 2005, Pages 109-114
Journal: Ultrasound in Medicine & Biology - Volume 31, Issue 1, January 2005, Pages 109-114
نویسندگان
Ryo Otsuka, Kana Fujikura, Kumiko Hirata, Todd Pulerwitz, Yukiko Oe, Takeki Suzuki, Robert Sciacca, Charles Marboe, Jie Wang, Daniel Burkhoff, Robert Muratore, Frederic L. Lizzi, Shunichi Homma,