کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
10736782 | 1045778 | 2005 | 26 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Functional senescence in Drosophila melanogaster
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
کلمات کلیدی
Negative geotaxisolfaction - بویاییReproduction - تولید مثل یا زادآوریMemory - حافظهLocomotion - حرکتBehavior - رفتارBiochemistry - زیستشیمی، بیوشیمی، شیمی حیاتAging - سالخوردگیHeart - قلب Metabolism - متابولیسم Review - مرورImmunity - مصونیتStress resistance - مقاومت در برابر استرسFruit flies - میوه مگسLearning - یادگیری
موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
سالمندی
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
The fruit fly Drosophila melanogaster is one of the principal model organisms used for studying the biology of aging. Flies are well suited for such studies for a number of reasons. Flies develop to adulthood quickly, have a relatively short life span, and are inexpensive to house. Most of the fly genome has been sequenced, powerful genetic tools are available to manipulate it, and most fly genes have obvious homologues in mammals. While the majority of aging studies in flies have focused on regulation of life span, the fly is emerging as a powerful model system for investigating the biology that underlies age-related functional decline. Key to the use of flies in this way is the striking number of parallels between functional senescence in Drosophila and humans. Here, we review age-related functional declines in Drosophila, human correlates of these age-related declines, and common mechanisms that influence longevity and specific aspects of functional senescence in flies.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Ageing Research Reviews - Volume 4, Issue 3, August 2005, Pages 372-397
Journal: Ageing Research Reviews - Volume 4, Issue 3, August 2005, Pages 372-397
نویسندگان
Michael S. Grotewiel, Ian Martin, Poonam Bhandari, Eric Cook-Wiens,