Age‐related expression, enzymatic solubility and modification with advanced glycation end‐products of fibrillar collagens in mouse lung

► Changes in the extracellular matrix essentially contribute to lung aging. ► We examine amount and post-translational modifications with glycation end-products in fibrillar collagens from mouse lung. ► Aging causes a lower total amount and higher load with glycation end-products of lung collagens. ► Higher load with glycation end-products is associated with lower enzymatic solubility of lung collagens. ► Not all changes occur gradually with higher age.