Inflammation-induced protein carbonylation contributes to poor prognosis for cholangiocarcinoma

► In liver fluke-associated cholangiocarcinoma tissues, inflammation resulted in carbonylated proteins. ► Carbonylation of serotransferrin may be involved in iron accumulation in cholangiocarcinoma tissues. ► Carbonylation of serotransferrin, HSP70.1, and A1AT correlated with a poor prognosis.