کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
10748204 1050266 2016 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Intrinsic and extrinsic mechanical properties related to the differentiation of mesenchymal stem cells
ترجمه فارسی عنوان
خصوصیات مکانیکی و بیرونی مرتبط با تمایز سلول های بنیادی مزانشیمی
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی زیست شیمی
چکیده انگلیسی
Diverse intrinsic and extrinsic mechanical factors have a strong influence on the regulation of stem cell fate. In this work, we examined recent literature on the effects of mechanical environments on stem cells, especially on differentiation of mesenchymal stem cells (MSCs). We provide a brief review of intrinsic mechanical properties of single MSC and examined the correlation between the intrinsic mechanical property of MSC and the differentiation ability. The effects of extrinsic mechanical factors relevant to the differentiation of MSCs were considered separately. The effect of nanostructure and elasticity of the matrix on the differentiation of MSCs were summarized. Finally, we consider how the extrinsic mechanical properties transfer to MSCs and then how the effects on the intrinsic mechanical properties affect stem cell differentiation.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Biochemical and Biophysical Research Communications - Volume 473, Issue 3, 6 May 2016, Pages 752-757
نویسندگان
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