Lasting inhibition of receptor-mediated calcium oscillations in pancreatic acini by neutrophil respiratory burst - A novel mechanism for secretory blockade in acute pancreatitis?

- Neutrophil modulation of pancreatic acini has not been investigated before.
- Neutrophil respiratory burst blocked calcium oscillations in pancreatic acini.
- Neutrophil respiratory burst had no effect on calcium oscillations in hepatocytes.
- Neutrophil respiratory burst leads to secretory blockade in pancreas.