کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
10758960 1050415 2013 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
GnRH neuron type-specific transcriptome analysis by laser captured single-cell microarray in the medaka
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی زیست شیمی
پیش نمایش صفحه اول مقاله
GnRH neuron type-specific transcriptome analysis by laser captured single-cell microarray in the medaka
چکیده انگلیسی
Most vertebrates possess at least two gonadotropin-releasing hormone (GnRH) neuron types. To understand the physiological significance of the multiple GnRH systems in the brain, we examined three GnRH neuron type-specific transcriptomes using single-cell microarray analyses in the medaka (Oryzias latipes). A microarray profile of the three GnRH neuron types revealed five genes that are uniquely expressed in specific GnRH neuron types. GnRH1 neurons expressed three genes that are homologous to functionally characterised genes, GnRH2 neurons uniquely expressed one unnamed gene, and GnRH3 neurons uniquely expressed one known gene. These genes may be involved in the modulation or maintenance of each GnRH neuron type.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Biochemical and Biophysical Research Communications - Volume 435, Issue 4, 14 June 2013, Pages 562-566
نویسندگان
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