α-Lipoic acid attenuates coxsackievirus B3-induced ectopic calcification in heart, pancreas, and lung

► CVB3-infected mice showed ectopic calcification in heart, pancreas, and lung. ► CVB3 infection induced inflammatory and apoptotic tissue damage. ► CVB3 infection led to osteogenic gene induction. ► α-Lipoic acid attenuates CVB3-induced calcification by inhibiting osteogenic signals.