The transcription factor Snail enhanced the degradation of E-cadherin and desmoglein 2 in oral squamous cell carcinoma cells

► Stable Snail transfectants (Snail/HSC-4) were generated. ► The downregulation of E-cadherin and desmoglein 2 was detected in Snail/HSC-4. ► E-cadherin and desmoglein 2 rapidly degraded in Snail/HSC-4 cells. ► The degradation of E-cadherin, but not desmoglein 2, was inhibited by dynasore.