Insulin-like growth factor-1 induces MUC8 and MUC5B expression via ERK1 and p38 MAPK in human airway epithelial cells

► IGF-1 is implicated in modulation of mucin secretion. ► IGF-1 induces MUC8 and MUC5B expression. ► IGF-1 induced MUC8 and MUC5B expression is regulated through ERK1 and p38 MAPK.