Acidic leucine-rich nuclear phosphoprotein 32 family member B (ANP32B) contributes to retinoic acid-induced differentiation of leukemic cells

► ANP32B was down-regulated during ATRA-induced leukemic cell differentiation. ► Knockdown of ANP32B enhanced ATRA-induced leukemic cell differentiation. ► Ectopic expression of ANP32B inhibited ATRA-induced leukemic cell differentiation. ► ANP32B inhibited ATRA activated transcriptional activity of RARα.