MiR-30c: A novel regulator of salt tolerance in tilapia

► miR-30c emerges as a kidney-enriched miRNA in tilapia. ► miR-30c expression is dynamically regulated by salt stress. ► miR-30c loss of function leads to an inability to respond to osmotic stress. ► HSP70 is identified as one of the direct regulatory targets of miR-30c.