Human peroxiredoxin 1 modulates TGF-β1-induced epithelial-mesenchymal transition through its peroxidase activity

► hPrx1 protein level regulates E-cadherin expression. ► hPrx1 knockdown blocks TGF-β1-induced EMT and cell migration. ► hPrx1 regulates E-cadherin expression through its peroxidase activity. ► hPrx1 downregulation suppresses Snail and Slug expression.